Beauty Buzzword: Glutathione

Some time ago, we shared some information on protecting your skin from the elements using antioxidants. But as you know, not all antioxidants are created equal.

If you haven’t already heard about glutathione, here’s your quick primer on the extraordinary antioxidant that’s set to make waves in the skincare world in 2012.

Antioxidants as free radical fighters

As the cells in our body perform their everyday functions, they incidentally create free radicals. These byproducts accumulate over time and become progressively more detrimental to our health.

In the context of aging, we know that free radical damage is a significant contributor to unsightly skin issues such as wrinkles, dark under eye circles, and age spots.

This is where antioxidants come in. We can use these powerful molecules to offset the negative effects of free radicals. One way to do this is by consuming a diet that includes antioxidant-rich fruits and vegetables – but that’s not the only way, especially since this doesn’t directly target skin cells.

Glutathione: the master antioxidant

Our cells are also able to produce their own antioxidants. Because glutathione is widely considered to be the strongest, it is also known as the “master” antioxidant.

Glutathione detoxifies our body of toxins and pollutants, increases our energy, repairs DNA damage, and optimizes our immune system. Imagine how that power would positively affect our skin, the body’s largest organ.

The body produces glutathione naturally, but certain compounds have been scientifically proven to encourage our cells to produce more of it. This is an important concept to consider in regards to caring for our skin, particularly as we age, since our body accumulates free radicals over time.

Fortunately, there are now products on the market that are able to stimulate the body’s natural glutathione production. When applied directly to the skin, they are an effective way to reverse the signs of skin aging.

The role of glutathione in anti-aging skincare

Glutathione is the powerhouse antioxidant on which other antioxidants depend to function properly. Antioxidants commonly found in anti-aging skincare products, such as Vitamins C and E and CoQ10, are less effective without glutathione.

A recent study published in the scientific journal, Fitoterapia, showed that Schisandrin B increased glutathione production at the cellular level. This means that these powerful compounds are able to help our cells naturally produce more glutathione to attack free radicals.

Schisandrin B is derived from the Schisandra berry, an herb commonly used in traditional Chinese medicine (TCM). Extracts from the Schisandra berry have been proven to be safe and effective in topical cosmetic applications. In over two decades of research and development, Glissandra Skincare has identified and isolated the most potent compounds from the Schisandra berry for use in its advanced anti-aging skincare products.

Keep your skin looking young, healthy, and beautiful

Do your skincare products promote the health of your skin by stimulating skin cells to produce glutathione? Can you find Schisandrin B on the ingredient list of the products you’re currently using? If you’re constantly struggling to fight aging skin, consider how much more effective it would be if your body was able to do more on its own.

Glutathione is changing anti-aging skincare. By taking a holistic, health-focused approach to caring for our skin, beautiful, younger-looking skin is finally within our reach.

References

Chiu PY, PY Lam, Yan CW, Ko KM. Schisandrin B protects against solar irradiation-induced oxidative injury in BJ human fibroblasts. Fitoterapia 2011; 82: 682-691.

Quirin, Dr. K. W. et al. Supercritical Schisandra Extracts – a New Concept for Personal Care Cosmetics. Cosmetic Science Technology, 2008.

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A holistic approach to caring for your aging skin

We’ve come to accept the signs of skin aging – wrinkles and expression lines, droopy eyelids, age spots, dark circles, dry skin, enlarged pores, sagging skin, and more (lucky us!) – as an inevitability.  Fortunately, the science of aging has advanced at a remarkable rate in recent years, providing tremendous insight into the causes of and effective solutions for our aging skin.

Numerous studies have identified five major causes of skin aging:

  1. Mitochondrial decay
  2. Inflammation
  3. Oxidative (free-radical induced) damage
  4. Depletion of cellular components, such as collagen and elastin
  5. Adverse external factors

In light of this, it would make sense that your skincare regimen be equipped to combat all causes of skin aging – especially the leading cause, mitochondrial decay – through a comprehensive, holistic approach.  Many anti-aging skincare products contain some combination of common ingredients, such as peptides, antioxidants, and hyaluronic acid, but they don’t stand up to all causes of skin aging simultaneously.  Neglecting even one cause renders the entire approach significantly less effective.  You wouldn’t go into battle with a hole in your armor, would you?

We understand that the condition of our skin as we age, whether we retain our young and healthy look, is influenced in part by genetics and also by environmental factors, which is fantastic if you’ve been blessed with good genes.  But while you can’t control the former, the good news for everyone is that you can control your exposure to adverse external factors, such as the sun, pollution, smoking and poor nutrition.  Avoiding these, while maintaining a conscientious skincare regimen that addresses all causes of skin aging, are easy steps you can take to control your skin’s aging process.

Nature’s contribution to advanced skincare: the Schisandra berry

By now, you’ve likely heard the growing buzz about the Schisandra berry, which is finally beginning to get the widespread attention it deserves, outside the scientific community. It is not just the next disposable “superberry”; Schisandra has been proven to have a significant, positive effect on aging skin.

The Schisandra berry has long been recognized as one of the 50 fundamental herbs of traditional Chinese medicine, and as the key to maintaining youth and radiance. It is now regarded as a vital adaptogen that helps the body achieve a balanced state and adapt to physical, mental, environmental and other stresses.

The Schisandra berry has exciting qualities and applications relating to its status as an adaptogen. It helps the body’s cells maintain and normalize the optimum conditions for their vital functioning. The Schisandra berry is naturally rich in antioxidants, and research suggests that it acts as an antioxidant-site stimulator. In this role, it has been seen to increase antioxidant activity throughout the body, helping fight free radical damage not only by providing its own antioxidants, but also by helping to stimulate antioxidants already present in the body – unlike other, supposed “superberries”.

So how does this affect our skin as we age?

Aging is a phenomenon that occurs in the body’s cells. Its effects are more apparent on the skin, body’s largest organ, and especially noticeable on the face. Aging brings about the depletion of cellular components (such as collagen, hyaluronic acid, etc.), oxidative damage, and inflammation – causing a loss of elasticity, pigmentation, radiance, and other visible signs of aging.

According to extensive research, Schisandra has been found to be “a safe and effective ingredient for the prevention and treatment of hyperproliferative and inflammatory skin conditions and offers a new concept for personal care cosmetics” (Quirin et al.).

However, concentrations of the key compounds, (-) Schisandrin B and Schisandrin A, in the original berries are minute. Ground Schisandra berries, berry juice, or Schisandra extracts collected by ordinary methods contain insignificant amounts of the potent compounds, thereby limiting the benefits to the skin. It is only through a proprietary extraction process that the anti-aging properties of the Schisandra berry can be absorbed by the skin.

Consumer Reports rates anti-wrinkle serums

Earlier this month, Consumer Reports released the findings of their recent anti-wrinkle serum tests. The verdict: that the products they evaluated fell short on their claims. Citing inconsistent results and only minor improvements to the wrinkles of their research subjects, the organization all but dismissed anti-aging products entirely. If readers caught only the headlines, they’d find themselves considerably misinformed about the efficacy of certain products available on the market today.

It’s difficult to argue with some of the points brought up in the report, which suggests that consumers focus on moisturizing and sun protection. However, Consumer Reports neglects to investigate the reason why the serums they tested failed: the products don’t necessarily address anti-aging holistically. It is a stretch to imply that anti-wrinkle serums don’t work; after all, Consumer Reports tested only nine well-known brands, none of which take a comprehensive approach by targeting all accepted causes of skin aging.

Scientific research in the area of gerontology has found that a number of factors contribute to skin aging, including inflammation, external adverse environmental factors, and the depletion of cellular components, such as collagen, elastin, and hyaluronic acid. Oxidative (free radical-induced) damage is often cited as a culprit, and products are loaded with antioxidants accordingly, despite their limited ability to produce results.

Scientists have now discovered the fundamental cause of skin aging: mitochondrial decay. For that reason, an effective anti-aging serum must include ingredients to address all causes of skin aging, but particularly mitochondrial decay. Fortunately for consumers, potent extracts from the schisandra berry have been proven to be effective in reversing age-related mitochondrial deterioration – so a real anti-wrinkle serum, one that lives up to its promises, does indeed exist.

Theories of aging: What you need to know

A recent article published by DailyBeauty explored five well-known theories of aging: inflammation, lifestyle, hormones, antioxidants, and detoxification. Though all are worthy of discussion, perhaps the most important theory, mitochondrial decay, was not mentioned. This dark horse in the race against skin aging – and indeed aging more generally – deserves the attention of women who are motivated to look and feel their very best at every age.

The mechanism of aging has long been an area of intensive research, and although a number of theories have been proposed, mitochondrial decay has widely become regarded as the leading cause of skin aging.

The concept may sound complicated, but it is surprisingly simple. Mitochondria are the energy-producing organelle of every cell. Cells make up every organ and all living cells have mitochondria. In fact, there are thousands of mitochondria per cell. Their primary job is to generate ATP, or fuel, through various energy cycles that involve nutrients and vitamins. ATP is needed for every movement, thought and action we make, yet very little ATP can be stored in the body.

In the natural process of oxidation (turning oxygen into energy), the mitochondria generate free radicals – highly reactive, unstable molecules that cause damage to healthy cells, leading to internal aging as well as the appearance of visible signs of external aging. As we age, the mitochondria become larger, less efficient and fewer in number. As such, ATP production declines and may eventually lead to cell death.

As organs cannot borrow energy from one another, the efficiency of each organ’s mitochondria is essential to its repair processes and functions. If an organ’s mitochondria fail, then so does that organ. The skin is the largest organ in the body, so the enhancement and protection of actual mitochondrial function is instrumental in preventing and slowing skin aging.